Sources and mechanisms of combined heavy-metal and antibiotic resistance traits in bacteria
DOI:
https://doi.org/10.24193/subbb.2017.1.07Keywords:
agriculture, antibiotic resistance, aquaculture, heavy metal resistance.Abstract
Nowadays, antibiotic resistance poses a great threat to the health of the individuals worldwide. In this context, scientific interest on how bacteria adapt in stress-related environmental conditions like those enriched in heavy metals and how the heavy-metal adaptive mechanism influence the antibiotic resistance is increasing. It was noted that the simultaneous use of heavy metals and antibiotics in agriculture and aquaculture might positively impact the dissemination of the antibiotic resistance genes in the environment. Current knowledge on the sources of simultaneous pollution with heavy metals and antibiotics, the co-occurrence of heavy-metal and antibiotic resistance traits in bacteria altogether with physiological mechanism underlying this phenomenon are overviewed.
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